[HTML][HTML] A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models

A Cheng, W Jia, I Kawahata, K Fukunaga - EBioMedicine, 2021 - thelancet.com
… ; targeted inhibition of the two proteins may confer potential therapeutic effects in MS … mouse
model (experimental autoimmune encephalomyelitis [EAE] mice), suggesting novel protein

[HTML][HTML] Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages

Y Xiao, L Shu, X Wu, Y Liu, LY Cheong, B Liao, X Xiao… - JCI insight, 2021 - ncbi.nlm.nih.gov
… Here we show that circulating fatty acid binding protein 4 (… autoimmune
encephalomyelitis/multiple sclerosis (19–21). FABP4-deficient mice exhibit a lower incidence of …

The Fabp5/calnexin complex is a prerequisite for sensitization of mice to experimental autoimmune encephalomyelitis

T Paskevicius, J Jung, M Pujol, P Eggleton… - The FASEB …, 2020 - Wiley Online Library
… -tail domain of Canx in conferring sensitivity to EAE induction, … protein (psoriasis-associated
fatty acid-binding protein [PA-… in epidermal-type fatty acid binding protein-deficient mice. J …

[HTML][HTML] Fatty acid-binding proteins: their roles in ischemic stroke and potential as drug targets

Q Guo, I Kawahata, A Cheng, W Jia, H Wang… - International journal of …, 2022 - mdpi.com
… response in an experimental autoimmune encephalomyelitis (EAE) mouse model of … death
in a myocardial infarction mouse model, whereas deficiency in FABP3 can effectively prevent …

Importance of fatty acid binding proteins in cellular function and organismal metabolism

LB Agellon - Journal of Cellular and Molecular Medicine, 2024 - Wiley Online Library
… to experimental autoimmune encephalomyelitis (EAE) induction, a … mouse strains: one that
is deficient of the cytosolic Fabp5 … As mentioned earlier, loss of Fabp5 conferred protection

[HTML][HTML] Impact of fatty acid-binding proteins in α-synuclein-induced mitochondrial injury in synucleinopathy

A Cheng, W Jia, I Kawahata, K Fukunaga - Biomedicines, 2021 - mdpi.com
… , in experimental autoimmune encephalomyelitis (EAE) in a mouse model of MS, the deficiency
of FABP5 indicated a protective effect from the development of EAE [129,130]. Dendritic …

[HTML][HTML] The biological functions and regulatory mechanisms of fatty acid binding protein 5 in various diseases

B Xu, L Chen, Y Zhan, KNS Marquez, L Zhuo… - Frontiers in cell and …, 2022 - frontiersin.org
… Interestingly, peritoneal macrophages isolated from FABP5-deficient mice exhibited a clear
… inflammatory autoimmune diseases such as experimental autoimmune encephalomyelitis (…

Calnexin and fatty acid binding protein 5 (Fabp5) complex in the blood-brain barrier

T Paskevicius - 2022 - era.library.ualberta.ca
… sensitization of mice to experimental autoimmune encephalomyelitis. … Deficiency of fatty
acid-binding proteins in mice confers protection from development of experimental autoimmune

[HTML][HTML] Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator‐activated receptor γ

M El Kharbili, K Aviszus, SK Sasse, X Zhao… - The FASEB …, 2022 - ncbi.nlm.nih.gov
… However, we have shown that FABP5‐deficient mice develop increased inflammation following
influenza A infection that persists long after wild type mice recovery, 23 likely indicating a …

[HTML][HTML] Salivary and lacrimal gland alterations of the epidermal fatty acid-binding protein (E-FABP) in non-obese diabetic mice

M Dogru, T Kojima, C Simsek, T Nagata… - International Journal of …, 2022 - mdpi.com
proteins and their relation to the pathogenesis of dry eye disease, we chose to use the NOD
mouse (a model mouse of … in the NOD mice were also compared with those in the WT mice. …